INSTITUTO DE PESQUISAS ENERGÉTICAS E NUCLEARES Repositório Digital da Produção Técnico Científica Biblioteca Terezine Arantes Ferraz

 

Publicações do autor   CARLOS ROBERTO JORGE SOARES    depositadas no Repositório Digital/IPEN - Total : 122 28/11/2024 04:54:25
Seq	Ano	Ipen_doc	Tipo	Circ.	Título
1	2024	30399	Artigo de periódico	Internacional	The pattern of GH action in the mouse brain
2	2024	30609	Texto completo de evento	Internacional	Radiolabeling of porcine, murine growth hormone and a potential antagonist G118R-mGH for biodistribution study
3	2024	30615	Texto completo de evento	Internacional	The role of Prolactin (PRL) in activating the signaling pathways of the Jak STAT complex as a potential candidate in radioresistant MDAMB-231 cells in 3D cultures
4	2023	29600	Artigo de periódico	Internacional	Molecular cloning and AlphaFold modeling of thyrotropin (ag-TSH) from the Amazonian fish Pirarucu (Arapaima gigas)
5	2023	29601	Artigo de periódico	Internacional	Isolation and characterization of the Arapaima gigas growth hormone (ag-GH) cDNA and three-dimensional modeling of this hormone in comparison with the human hormone (hGH)
6	2023	30248	Resumo de eventos científicos	Internacional	Estabelecimento de um consórcio entre CEMIB, IPEN e Instituto Butantan, para a capacitação, implantação e desenvolvimento da técnica de criopreservação e reprodução assistida de animais de laboratório
7	2022	28435	Artigo de periódico	Internacional	Biophysical properties of electrospun chitosan-grafted poly(lactic acid) nanofibrous scaffolds loaded with chondroitin sulfate and silver nanoparticles
8	2022	28694	Artigo de periódico	Internacional	In vitro cytotoxic data on Se-methylselenocysteine conjugated to dendritic poly(glycerol) against human squamous carcinoma cells
9	2021	27769	Artigo de periódico	Internacional	Periplasmic synthesis and purification of the human prolactin antagonist Δ1‑11‑G129R‑hPRL
10	2021	28344	Artigo de periódico	Internacional	Microfluidic caging lipase in hyperbranched polyglycerol microcapsules for extracorporeal treatment of enzyme pancreatic insufficiency
11	2021	28628	Resumo de eventos científicos	Internacional	SARS-CoV-2 Spike (S) glycoprotein expression, purification and characterization in suspension human embryonic kidney cells 293
12	2020	27524	Iniciação Científica	Nacional	Avaliação do cultivo de células CHO adaptadas a suspensão em diferentes formulações de meios de cultura comerciais livres de soro
13	2019	25193	Artigo de periódico	Internacional	Suppression of prolactin secretion partially explains the antidiabetic effect of bromocriptine in ob/ob mice
14	2019	26443	Artigo de periódico	Internacional	Expression of glycosylated human prolactin in HEK293 cells and related N‑glycan composition analysis
15	2019	26487	Artigo de periódico	Internacional	Poly(3-hydroxi-butyrate-co-3-hydroxy-valerate) (PHB-HV) microparticles loaded with holmium acetylacetonate as potential contrast agents for magnetic resonance images
16	2019	26587	Iniciação Científica	Nacional	Expressão e caracterização da tireotrofina humana (hTSH) recombinante em células CHO cultivadas em suspensão
17	2019	26605	Iniciação Científica	Nacional	Purificação de antagonista de prolactina expresso em bactérias Escherichia coli
18	2019	26714	Livro	Nacional	O IPEN e a saúde
19	2019	26765	Resumo de eventos científicos	Internacional	Expression of the human prolactin antagonist delta 1-11 G129R-PRL in E. coli periplasm
20	2018	24236	Artigo de periódico	Internacional	Determination of recombinant Interferon-α2 in E. coli periplasmic extracts by reversed-phase high-performance liquid chromatography
21	2018	24240	Artigo de periódico	Internacional	Human thyroid-stimulating hormone synthesis in human embryonic kidney cells and related N-glycoprofiling analysis for carbohydrate composition determination
22	2018	24735	Artigo de periódico	Internacional	Brain STAT5 signaling modulates learning and memory formation
23	2018	25046	Artigo de periódico	Internacional	High production and optimization of the method for obtaining pure recombinant human prolactin
24	2018	25059	Artigo de periódico	Internacional	Development and characterization of polymeric microparticle of poly(D,L-lactic acid) loaded with holmium acetylacetonate
25	2018	25186	Iniciação Científica	Nacional	Purificação e caracterização da tireotrofina humana (hTSH) expressa em células de rim de embrião humano (Expi293F™) em suspensão
26	2018	25192	Artigo de periódico	Internacional	Porphyrins are increased in the faeces of patients with prostate cancer
27	2017	22681	Artigo de periódico	Internacional	Distribution of growth hormone-responsive cells in the mouse brain
28	2017	22995	Artigo de periódico	Internacional	N-Glycoprofiling analysis for carbohydrate composition and site-occupancy determination in a poly-glycosylated protein: human thyrotropin of different origins
29	2017	22999	Artigo de periódico	Internacional	Expression, purification and characterization of the authentic form of human growth hormone receptor antagonist G120R-hGH obtained in Escherichia coli periplasmic space
30	2017	24118	Iniciação Científica	Nacional	Expressão da tireotrofina humana (hTSH) em células de rim de embrião humano (Expi293F™) cultivadas em suspensão
31	2017	24264	Resumo de eventos científicos	Internacional	Transient expression of recombinant human prolactin and thyrotropin in human embryonic kidney (Expi293FTM) suspension cells
32	2017	24265	Resumo de eventos científicos	Internacional	Expression of human prolactin in HEK293T using different transfection reagents
33	2017	24397	Resumos em periódicos	Internacional	Carbohydrate composition and site-occupancy determination in pituitary and recombinant preparations of human thyrotropin
34	2017	26981	Resumo de eventos científicos	Internacional	GH controls glycemia and metabolic adaptations to starvation via neurons that express the leptin receptor
35	2016	22997	Artigo de periódico	Internacional	Conceptual proposal of a facility design for accommodating minipigs for pharmaceutical and radiopharmaceutical research
36	2016	23977	Resumo de eventos científicos	Nacional	Role of prolactin in the anti-diabetic effects of bromocriptine: possible action through estrogen receptor alpha in the brain
37	2015	20704	Artigo de periódico	Internacional	N-glycoprofiling analysis in a single glycoprotein model: a comparison between recombinant and pituitary glycosylated human prolactin
38	2015	21362	Texto completo de evento	Nacional	Expressão do antagonista de receptor do hormônio do crescimento humano G120R-hGH no espaço periplásmico de Escherichia coli e sua caracterização físico-química
39	2015	21449	Iniciação Científica	Nacional	Expressão do antagonista de receptor do hormônio do crescimento humano G120R-hGH no espaço periplástico de Escherichia coli e sua caracterização físico-química e biológica
40	2015	22638	Texto completo de evento	Internacional	Conceptual proposal of a facility for handlings of minipigs for pharmaceutical and radiopharmaceutical research
41	2014	20269	Resumos em periódicos	Internacional	Expression and characterization of mouse prolactin (mPRL) in CHO dhfr-cells
42	2014	20291	Resumos em periódicos	Internacional	The influence of Escherichia coli cultivation temperature on interferon alpha 2a expression (IFN-'alfa'2a)
43	2014	20664	Resumo de eventos científicos	Internacional	N-glycoprofiting analysis in a single ghycoprotein model: Glycosylated human prolactin
44	2014	22311	Resumos em periódicos	Internacional	N-glycoprofiling analysis in a simple glycoprotein model: glycosylated human prolactin
45	2014	22335	Resumo de eventos científicos	Internacional	Uncovering the mechanism of action of the anti-diabetic effects of bromocriptine: the role of prolactin
46	2013	18812	Artigo de periódico	Internacional	Isolation of the pituitary gonadotrophic 'alpha'-subunit hormone of the giant amazonian fish: pirarucu (Arapaima gigas)
47	2013	19791	Resumo de eventos científicos	Internacional	A comparison between the oligosaccharide structures of native and recombinant glycosylated human prolactin obtained from CHO cells
48	2013	19796	Texto completo de evento	Nacional	The influence of Escherichia coli cultivation temperature on interferon alpha expression (IFN-'alfa'2a)
49	2013	19797	Resumo de eventos científicos	Nacional	Expression and characterization of mouse prolactin (mPRL) in CHO dhfr-cells
50	2012	18110	Artigo de periódico	Internacional	Expression, purification, and characterization of authentic mouse prolactin obtained in Escherichia coli periplasmic space
51	2012	18119	Resumo de eventos científicos	Nacional	Purification of glycosylated human prolactin from CHO cells adapted to serum-free suspension culture, by reverse=phase HPLC
52	2012	18120	Resumo de eventos científicos	Nacional	Expression, purification, and characterization of a CHO-derived mouse prolactin receptor antagonist S177D-mPRL produced in serum-free medium
53	2012	18184	Artigo de periódico	Internacional	Laboratory production of human prolactin from CHO cells adapted to serum-free suspension culture
54	2012	18704	Resumo de eventos científicos	Nacional	Glicoprotein alpha characterization of the Amazonia fis (Arapaima gigas)
55	2012	21804	Iniciação Científica	Nacional	Síntese e caracterização de prolactina de camundongos em células CHO
56	2011	16538	Artigo de periódico	Internacional	Improved bioprocess with CHO-hTSH cells on higher microcarrier concentration provides higher overall biomass and productivity for rhTSH
57	2011	16585	Resumo de eventos científicos	Nacional	First expression of the antagonist of mouse prolactin (S177D-mPRL) by adherent dhfr-CHO cell using p658 vector
58	2011	17127	Artigo de periódico	Internacional	Novel series of sup(177)Lu-labeled bombesin derivatives with amino acidic for selective targeting of human PC-3 prostate tumor cells
59	2011	17621	Resumo de eventos científicos	Internacional	A practical and fast adaptation of CHO cells expressing human prolactin to grow in suspension and its application to laboratory production
60	2011	17663	Texto completo de evento	Nacional	Influência de meios de cultivo comerciais na produção laboratorial de prolactina humana sintetizada por células CHO cultiadas em suspensão
61	2010	14975	Artigo de periódico	Internacional	Synthesis, purification and characterization of recombinant glycosylated human prolactin (G-hPRL) secreted by cycloheximide-treated CHO cells
62	2010	15555	Artigo de periódico	Internacional	Enhancement of human prolactin synthesis by sodium butyrate addition to serum-free CHO cell culture
63	2010	15608	Resumo de eventos científicos	Nacional	Physico-chemical and biological characterization of glycosylated human prolactin produced at IPEN
64	2010	15978	Resumo de eventos científicos	Nacional	Two-step purification of mouse prolactin expressed in the periplasmic space of Escherichia coli
65	2010	16240	Iniciação Científica	Nacional	Análise da expressão de prolactina humana em celulas CHO tratadas com butirato de sódio
66	2010	16350	Artigo de periódico	Internacional	Lymphocytic prolactin does not contribute to systemic lupus erythematosus hyperprolactinemia
67	2009	13059	Artigo de periódico	Internacional	Evaluation of radioinduced damage and repair capacity in human breast cancer cells, MCF-7 and T-47D
68	2009	14063	Artigo de periódico	Internacional	A molecular mimic of phosphorylated prolactin (S179D PRL) secreted by eukaryotic cells has a conformation with an increased positive surface charge compared to that of unmodified prolactin
69	2009	14128	Texto completo de evento	Nacional	Expressão de prolactina de camundongos no espaço periplastico de Escherichia coli
70	2009	14342	Texto completo de evento	Nacional	Produção em escala laboratorial de prolactina humana em células CHO adaptadas para o crescimento em suspensão
71	2008	12980	Artigo de periódico	Internacional	Distinct human prolactin (hPRL) and growth hormone (hGH) behavior under bacteriophage lambda Psub(L) promoter control: temperature plays a major role in protein yields
72	2008	16598	Resumo de eventos científicos	Nacional	Purification and characterization recombinant glycosylated human prolactin synthesized in cho cells
73	2008	16599	Resumo de eventos científicos	Nacional	Influence of activation temperature on the degradation of recombinant proteins in E.coli
74	2008	16600	Resumo de eventos científicos	Internacional	Cycloheximide increases the synthesis of recombinant glycosylated human prolactin (G-hPRL) secreted by CHO cells
75	2008	22244	Iniciação Científica	Nacional	Aplicação dos bioensaios com células Ba/F3-LLP e Nb2 na determinação da potência biológica da prolactina humana
76	2007	11949	Texto completo de evento	Internacional	Evaluation of radioinduced damage an repair capacity in human breast cancer cells, MCF-7 and T-47D
77	2007	12448	Resumo de eventos científicos	Internacional	Bioactive and properly folded prolactin is obtained in E.coli in a pilot bioreactor at 37 graus C by constitutive expression based on the unrepressed ?Psub(L) promoter
78	2007	12449	Resumo de eventos científicos	Internacional	The effect of cycloheximide on the glycosylation of recombinant human prolactin synthesized in cho cells
79	2007	12450	Resumo de eventos científicos	Internacional	Induction of micronucleus in breast cancer cells by sup(60)Co gamma radiation
80	2007	22087	Iniciação Científica	Nacional	Aplicação do bioensaio Ba/F3-LLP na determinação da potência biológica da prolactina humana glicosiladfa (G-hPRL)
81	2006	11377	Artigo de periódico	Internacional	Human macroprolactin displays low biological activity via its homologous receptor in a new sensitive bioassay
82	2006	11417	Artigo de periódico	Internacional	Physico-chemical and biological characterizations of two human prolactin analogs exhibiting controversial bioactivity, synthesized in chinese hamster ovary (CHO) cells
83	2006	11434	Resumo de eventos científicos	Nacional	The use of bacterioophage lambda Psub(L) as a constitutive promoter
84	2006	11435	Resumo de eventos científicos	Nacional	S179D prolactin (PRL) primarity uses the extrinsic pathway and MAPkinase signaling to induced apoptosis in human endothelial cells
85	2006	11490	Artigo de periódico	Internacional	Point mutation of serine 179 in the human Prolactin (PRL) affects recombinant protein expression, folding and secretion, abolishes PRL nickel (II)-binding and increases heparin binding capacities
86	2006	11501	Resumo de eventos científicos	Internacional	Human prolactin (hPRL) and growth hormone (hGH) distinct behavior under bacteriophage lamdda Psub(L) promoter control
87	2006	11502	Resumo de eventos científicos	Internacional	Point mutation of serine 179 in the human prolactin (PRL) affects recombinant protein expression, folding and secretion, abolishes PRL nickel (II)-binding and increases heparin binding capacities
88	2006	11548	Artigo de periódico	Internacional	High-level secretion of growth hormone by retrovirally transduced primary human keratinocytes
89	2005	11006	Resumo de eventos científicos	Internacional	Practical two-step purification of recombinant human prolactin and two analogous expressed by chinese hamster ovary (CHO) cells
90	2005	11009	Resumo de eventos científicos	Internacional	High-level secretion of growth hormone by retrovirally transduced primary human keratinocytes: prospects for an animal model of cutaneous gene therapy
91	2005	11011	Resumo de eventos científicos	Internacional	Reversed-phase high performance liquid chromatography (RP-HPLC) analysis and hydrophobicity studies of recombinant human pituitary hormones synthesized in E. coli and CHO cells
92	2004	10053	Resumo de eventos científicos	Internacional	Coculture studies Ba/F3-LP cells and HPRL, G129R-HPRL and S179D-HPRL secreting cho cells
93	2003	09785	Artigo de periódico	Internacional	Periplasmic expression of human growth hormone via plasmid vectors containing the lambdaPsub(L) promoter: use of HPLC for product quantification
94	2002	08537	Resumo de eventos científicos	Nacional	Approaches to maximizing the periplasmic expression in Escherichia coli of the human growth hormone gene from a vector containing the lambda Psub(L)
95	2002	08648	Artigo de periódico	Internacional	High-level expression of human thyroid-stimulating hormone in Chinese hamster ovary cells by co-transfection of dicistronic expression vectors followed by a dual-marker amplification strategy
96	2002	08649	Artigo de periódico	Internacional	Reversed-phase high-performance liquid chromatography method for the determination of prolactin in bacterial extracts and in its purified form
97	2001	07733	Resumo de eventos científicos	Nacional	Rec-hPRL production in E.coli periplasmic space with the use of a temperature sensible promoter
98	2001	07734	Resumo de eventos científicos	Nacional	Physico-chemical study on the First International Standard of Recombinant Human Prolactin, carried out at IPEN-CNEN/SP in collaboration with WHO
99	2000	06777	Tese	Nacional	Sintese de prolactina humana em celulas de ovario de hamster chines (CHO)
100	2000	06990	Resumo de eventos científicos	Nacional	Hollow fiber bioreactors for hormone production in CHO cells
101	2000	06993	Resumo de eventos científicos	Nacional	Utilization of di and tricistronic vectors for the expression of recombinant human thyrotropin (rec -hTSH) in CHO cells
102	2000	06994	Resumo de eventos científicos	Internacional	High level synthesis of recombinant human prolactin in CHO cells and identification of the 22 kDa fragment hPRLsub(11-199)
103	2000	06995	Resumo de eventos científicos	Internacional	A reversed-phase high -performance liquid chromatography (RP-HPLC) method for the determination of human prolactin (hPRL) in osmotic shock fluids and in purified preparations
104	2000	07063	Artigo de periódico	Internacional	High-level synthesis of human prolactin in Chinese hamster ovary cells
105	1999	07347	Artigo de periódico	Internacional	High-yield purification of biosynthetic human growth hormone secreted in Escherichia coli periplasmic space
106	1999	07722	Resumo de eventos científicos	Nacional	Expression of recombinant human thyrotropin (REC-hTSH) in CHO cells using dicistronic mRNA expression vectors with amplifiable markers
107	1999	07723	Resumo de eventos científicos	Nacional	Analysis of recombinant humam prolactin (REC-hPRL) directly in E.coli osmotic shock fluids
108	1998	06130	Artigo de periódico	Internacional	Synthesis and characterization of recombinant, authentic human prolactin secreted into the periplasmic space of Escherichia coli
109	1998	07720	Resumo de eventos científicos	Nacional	Purification of glycosylated and nonglycosylated recombinant human prolactin produced by chinese hamster ovary cells in a hollow fiber bioreactor
110	1997	06347	Resumo de eventos científicos	Nacional	Strategies for achieving high-level expression of recombinant human prolactin (hPRL) in E. coli
111	1996	04693	Resumo de eventos científicos	Nacional	Recombinant human growth hormone. Production and quality control
112	1996	04696	Resumo de eventos científicos	Nacional	Production and characterization of authentic human prolactin (hPRL) secreted in the periplasmic space of Escherichia coli
113	1996	04697	Resumo de eventos científicos	Nacional	A study of the efficiency of different types of bacterial expression vectors based on the 'lambda Psub(L)' and 'TAC' promoters
114	1995	05877	Resumo de eventos científicos	Nacional	Physicochemical immunological and biological characterization of recombinant human growth hormone
115	1995	06046	Dissertação	Nacional	Ensaio imunorradiometrico para a determinacao de proteinas bacterianas contaminantes em lotes de hormomio de crescimento humano recombinante produzido no IPEN-CNEN/SP
116	1995	06086	Resumo de eventos científicos	Nacional	Intra and interlaboratory evaluation of commercial recombinant thyrotropin for the preparation of radioassay reagents
117	1993	02159	Resumo de eventos científicos	Internacional	Radioimmunologic techniques used in quantitative and qualitative analyses of recombinant human growth hormone (rec-hGH) for E. coli contaminant proteins (ECP) and hGH-related forms determination
118	1992	01947	Resumo de eventos científicos	Nacional	Estudo das melhores condicoes na determinacao de proteinas de E.coli em produtos obtidos mediante tecnicas de DNA recombinante
119	1992	01948	Resumo de eventos científicos	Nacional	Immunoradiometric assay (IRMA) for the detection of E.coli proteins in recombinant human growth hormone prepared at IPEN-CNEN/SP
120	1991	03885	Resumo de eventos científicos	Nacional	Isolation and purification of biosynthetic human growth hormone expressed in transformed E.coli cells
121	1991	03907	Texto completo de evento	Internacional	Utilization of DNA-recombinant techniques for the preparation of radioimmunoassay reagents of pituitary hormones
122	1991	03910	Texto completo de evento	Internacional	In-house reagent preparation for the setting up of a magnetic immunoradiometric assay (IRMA) for hTSH