INSTITUTO DE PESQUISAS ENERGÉTICAS E NUCLEARES
Repositório Digital da Produção Técnico Científica
Biblioteca Terezine Arantes Ferraz
   

 
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Nome : PAOLO BARTOLINI

INSTITUTO DE PESQUISAS ENERGÉTICAS E NUCLEARES
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BARTOLINI, P.
BARTOLINI, PAOLO

 

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Publicações do autor depositadas no Repositório Digital/IPEN - Total : 304
Seq Ano Ipen_doc Tipo Circ. Título
1 2017 22995 Artigo de periódico I N-Glycoprofiling analysis for carbohydrate composition and site-occupancy determination in a poly-glycosylated protein: human thyrotropin of different origins
2 2016 21730 Artigo de periódico I Partial correction of the dwart phenotype by non-viral transfer of the growth hormone gene in mice: treatment age is critical
3 2016 22433 Artigo de periódico I Cytotogenic and dosimetric effects of sup(131)I in patients with differentiated thyroid carcinoma: comparison between stimulation with rhTSH and thyroid hormone withdrawal treatments
4 2016 22891 Artigo de periódico I Evaluation of an in vitro cell culture assay for the potency assessment of recombinant human erythropoietin
5 2016 22999 Artigo de periódico I Expression, purification and characterization of the authentic form of human growth hormone receptor antagonist G120R-hGH obtained in Escherichia coli periplasmic space
6 2016 23500 Artigo de periódico I Physical-chemical and biological characterization of different preparations of equine chorionic gonadotropin
7 2016 23969 Artigo de periódico I Effect of cold stress on physicochemical characteristics and biological activity of equine chorionic gonadotropin
8 2016 23977 Resumo de eventos científicos N Role of prolactin in the anti-diabetic effects of bromocriptine: possible action through estrogen receptor alpha in the brain
9 2015 20704 Artigo de periódico I N-glycoprofiling analysis in a single glycoprotein model: a comparison between recombinant and pituitary glycosylated human prolactin
10 2015 21241 Resumos em periódicos I Early treatment for growth hormone deficiency based on naked DNA administration in dwart mice allows efficient catch-up growth
11 2015 21356 Resumos em periódicos I Molecular cloning, characterization and phylogenetic analysis of pirarucu (Arapaima gigas) FSH and LH beta-subunits
12 2015 21362 Texto completo de evento N Express√£o do antagonista de receptor do horm√īnio do crescimento humano G120R-hGH no espa√ßo peripl√°smico de Escherichia coli e sua caracteriza√ß√£o f√≠sico-qu√≠mica
13 2015 21588 Cap√≠tulo de livro N Modelos de terapia g√™nica baseados na express√£o de horm√īnio de crescimento em c√©lulas humanas e na administra√ß√£o de DNA plasmidial em camundongos an√Ķes
14 2014 19955 Artigo de periódico I Effect of Brazilian propolis (AF-08) on genotoxicity, cytotoxicity and clonogenic death of Chinese hamster ovary (CHO-K1) cells irradiated with sup(60)Co gamma-radiation
15 2014 20061 Artigo de periódico I A novel homologous model for gene therapy of swarfism by non-viral transfer of the mouse growth hormone gene into immunocompetent dwarf mice
16 2014 20113 Artigo de periódico I Reversed-phase performance liquid chromatography as an alternative to animal bioassay for human thyrotropin potency determination
17 2014 20256 Resumos em periódicos I Effects of butyrate and manganese on productivity, sialylation, N-glycosylation site occupancy and biological properties of CHO-derived thyrotropin
18 2014 20269 Resumos em periódicos I Expression and characterization of mouse prolactin (mPRL) in CHO dhfr-cells
19 2014 20272 Artigo de periódico I Human adipose tissue derived pericytes increase life span in Utrnsup(tm1Ked) Dmdsup(mdx)/J mice
20 2014 20291 Resumos em periódicos I The influence of Escherichia coli cultivation temperature on interferon alpha 2a expression (IFN-'alfa'2a)
21 2014 20664 Resumo de eventos científicos I N-glycoprofiting analysis in a single ghycoprotein model: Glycosylated human prolactin
22 2014 22302 Resumo de eventos científicos I Efficient and non-invasive plasmid DNA administration into the tibialis cranialis muscle of dwarf mice
23 2014 22311 Resumos em periódicos I N-glycoprofiling analysis in a simple glycoprotein model: glycosylated human prolactin
24 2014 22335 Resumo de eventos científicos I Uncovering the mechanism of action of the anti-diabetic effects of bromocriptine: the role of prolactin
25 2013 18812 Artigo de periódico I Isolation of the pituitary gonadotrophic 'alpha'-subunit hormone of the giant amazonian fish: pirarucu (Arapaima gigas)
26 2013 18889 Artigo de periódico I Systemic delivery of human mesenchymal stromal cells combined with IGF-1 enhances muscle functional recovery in LAMA2sup(dy/2j) dystrophic mice
27 2013 19073 Resumo de eventos científicos N Growth parameter increase and Anti-hGH, Anti-mGH antibody determination in lit/lit mice after a single injection of naked DNA followed by electroporation
28 2013 19380 Texto completo de evento I Comparison of the cytogenetic effects of sup(131)I in patients with differentiated thyroid cancer with and without prior treatment with rhtsh
29 2013 19545 Artigo de periódico I Enhancement of human thyrotropin synthesis by sodium butyrate addition to serum-free CHO cell culture
30 2013 19796 Texto completo de evento N The influence of Escherichia coli cultivation temperature on interferon alpha expression (IFN-'alfa'2a)
31 2013 19797 Resumo de eventos científicos N Expression and characterization of mouse prolactin (mPRL) in CHO dhfr-cells
32 2013 19814 Resumo de eventos científicos I Phenotypic correction of dwarfism in immunodeficient dwarf mice following intramuscular hGH plasmid administration analyzed via different growth parameters
33 2013 19986 Resumos em periódicos N Ovarium response of rats and gilts submitted to different commercial equine chrionic gonadotropins (eCG)
34 2012 17740 Artigo de periódico I Qualitative and quantitative reversed-phase high performance liquid chromatographic analysis of glycoprotein hormones in the presence of a large excess of human serum albumin
35 2012 17741 Artigo de periódico I Validation of a stability-indicating RP-LC method for the assessment of recombinant human interleukin-11 and its correlation with bioassay
36 2012 17865 Artigo de periódico I Growth hormone response to growth hormone-releasing peptide-2 in growth hormone-deficient little mice
37 2012 18110 Artigo de periódico I Expression, purification, and characterization of authentic mouse prolactin obtained in Escherichia coli periplasmic space
38 2012 18119 Resumo de eventos científicos N Purification of glycosylated human prolactin from CHO cells adapted to serum-free suspension culture, by reverse=phase HPLC
39 2012 18120 Resumo de eventos científicos N Expression, purification, and characterization of a CHO-derived mouse prolactin receptor antagonist S177D-mPRL produced in serum-free medium
40 2012 18121 Resumo de eventos científicos N Complete RP-HPLC analysis of WHO International Standards
41 2012 18184 Artigo de periódico I Laboratory production of human prolactin from CHO cells adapted to serum-free suspension culture
42 2012 18276 Resumo de eventos científicos I An homologous model of gene therapy by in vivoadministration of a plasmid containing the mouse growth hormone gene in immunocompetent dwarf mice
43 2012 18345 Artigo de periódico I Growth responses following a single intra-muscular hGH plasmid administration compared to daily injections of hGH in dwarf mice
44 2012 18607 Resumo de eventos científicos N Ideal conditions for gene transfer through electroporation in dystrophic models for muscular dystrophies
45 2012 18608 Resumo de eventos científicos I Growth responses following a single intra-muscular hGH plasmid administration compared to daily injections of hGH in dwarf mice
46 2012 18702 Resumo de eventos científicos I Sodium butyrate greatly enhances human thyrotropin (hTSH) synthesis by serum-free CHO cell culture with alterations of the carbohydrate moiety
47 2012 18703 Resumo de eventos científicos I Quantitative analysis of different preparations of human thyrotropin (hTSH): a comparison between RP-HPLC and the in vivo bioassay based on thyroxine stimulaton mice
48 2012 18704 Resumo de eventos científicos N Glicoprotein alpha characterization of the Amazonia fis (Arapaima gigas)
49 2012 18926 Resumo de eventos científicos I Muscle spontaneous regeneration in dwarf mice treated with a bicistronic vector followed electrotransfer
50 2012 18927 Resumo de eventos científicos I Comparison of genomic and complementary hGH gene sequences utilized for electrotransfer in dwart mice
51 2011 16421 Resumo de eventos científicos N Growth parameters after intramuscular hGH plasmid administration compared to recombinant hGH injections in lit/scid mice
52 2011 16425 Artigo de periódico I A pilot study on potency determination of human follicle-stimulating hormone: A comparison between reversed-phase high-performance liquid chromatography method and the vivo bioassay
53 2011 16441 Resumo de eventos científicos I Glycosylation and pharmacokinetics of human thyrotropin
54 2011 16538 Artigo de periódico I Improved bioprocess with CHO-hTSH cells on higher microcarrier concentration provides higher overall biomass and productivity for rhTSH
55 2011 16585 Resumo de eventos científicos N First expression of the antagonist of mouse prolactin (S177D-mPRL) by adherent dhfr-CHO cell using p658 vector
56 2011 16586 Resumo de eventos científicos N RP-HPLC qualitative and quantitative analysis of glycoprotein hormones in the presence of high amounts of human serum albumin: hLH, hCG, hFSH and hTSH
57 2011 17367 Resumo de eventos científicos I Non-viral gene transfer to skin, muscle and liver for expression of growth homone
58 2011 17391 Capítulo de livro I Different ex vivo and direct in vivo DNA administration strategies for growth hormone gene therapy in dwarf animals
59 2011 17505 Resumo de eventos científicos I In vitro, ex vivo and in vivo recombinant growth hormone synthesis, for gene therapy applications
60 2011 17526 Resumo de eventos científicos N Growth parameters after intramuscular hGH plasmid administration compared to recombinant hGH injections in LIT/SCID mice
61 2011 17569 Artigo de periódico I Preclinical studies with umbilical cord mesenchymal stromal cells in different animal models for muscular dystrophy
62 2011 17621 Resumo de eventos científicos I A practical and fast adaptation of CHO cells expressing human prolactin to grow in suspension and its application to laboratory production
63 2011 17663 Texto completo de evento N Influência de meios de cultivo comerciais na produção laboratorial de prolactina humana sintetizada por células CHO cultiadas em suspensão
64 2010 14975 Artigo de periódico I Synthesis, purification and characterization of recombinant glycosylated human prolactin (G-hPRL) secreted by cycloheximide-treated CHO cells
65 2010 14984 Artigo de periódico I Analysis of human luteinizing hormone and human chorionic gonadotropin preparations of different origins by reversed-phase high-performance liquid chromatography
66 2010 15555 Artigo de periódico I Enhancement of human prolactin synthesis by sodium butyrate addition to serum-free CHO cell culture
67 2010 15564 Artigo de periódico I Long-term human growth hormone expression and partial phenotypic correction by plasmid-base gene therapy in an animal model of isolated growth hormone deficiency
68 2010 15598 Resumo de eventos científicos N Highly significant body weight increase of Lit/Scid mice after electrotransfer of hGH-coding plasmid DNA
69 2010 15608 Resumo de eventos científicos N Physico-chemical and biological characterization of glycosylated human prolactin produced at IPEN
70 2010 15978 Resumo de eventos científicos N Two-step purification of mouse prolactin expressed in the periplasmic space of Escherichia coli
71 2010 16102 Artigo de periódico I Human multipotent mesenchymal stromal cells from distinct sources show different in vivo potential to differentiate into muscle cells when injected in dystrophic mice
72 2010 16157 Resumo de eventos científicos N Reversed-phase higg-performance liquid chromatography characterization of human menopausal gonadotropin preparations
73 2010 16158 Resumo de eventos científicos N Physico-chemical quality control of human chrionic gonadotropin preparations
74 2010 16159 Resumo de eventos científicos N International collaborative study to establish the 2nd WHO International Standard of Human Recombinant Fillicle Stimulating Hormone for Bioassai
75 2010 16160 Resumo de eventos científicos N Charge isomer distribution of different pituitary and recombinant human thyrotropin (hTSH) preparations
76 2010 16350 Artigo de periódico I Lymphocytic prolactin does not contribute to systemic lupus erythematosus hyperprolactinemia
77 2010 16636 Resumo de eventos científicos N Enriquecimento de queratinócitos secretores de mGH em células-tronco mediante adesão rápida ao colágeno
78 2009 13059 Artigo de periódico I Evaluation of radioinduced damage and repair capacity in human breast cancer cells, MCF-7 and T-47D
79 2009 13827 Artigo de periódico I Efficient isolation of the subunits of recombinant and pituitary glycoprotein
80 2009 14063 Artigo de periódico I A molecular mimic of phosphorylated prolactin (S179D PRL) secreted by eukaryotic cells has a conformation with an increased positive surface charge compared to that of unmodified prolactin
81 2009 14065 Resumos em periódicos I Comparison of skeletal muscle potential of mesenchymal stem-cells from different sources injected in SJL mice
82 2009 14097 Texto completo de evento I Induction of chromosomal aberrations in human lymphocytes by fission neutrons
83 2009 14128 Texto completo de evento N Expressao de prolactina de camundongos no espaco periplastico de Escherichia coli
84 2009 14160 Resumo de eventos científicos I Indentity and integraty of 'alfa' and 'beta' - subunit of human thyrotropin prepared by prolonged acetic acid treatment
85 2009 14161 Resumo de eventos científicos I Comparison between CHO-derived thyrotropin containing 'alfa' 2,6 sialic acid linkages (hlsr-hTSH) and the conventional recombinant product
86 2009 14267 Artigo de periódico I Stable expression of a human-like sialylated recombinant thyrotropin in a chinese hamster ovary cell line expressing 'alfa'2,6-sialyltransferase
87 2009 14323 Resumo de eventos científicos N Avaliacao preliminar do efeito radioprotetor da propolis brasileira em celulas CHO-K1 irradiadas com Co-60 pelo ensaio do micronucleo
88 2009 14342 Texto completo de evento N Producao em escala laboratorial de prolactina humana em celulas CHO adaptadas para o crescimento em suspensao
89 2009 14344 Resumo de eventos científicos N Relacao dose-resposta para inducao de aberracoes cromossomicas por neutron de fissao em linfocitos humanos
90 2009 15154 Texto completo de evento I Protective effect of propolis on radiation-induced chromosomal damage on Chinese hamster ovary cells (CHO-K1)
91 2009 16651 Resumo de eventos científicos I Sustained hGH expression after electrotransfer of naked DNA into DWARF 'little!' mouse skeletal muscle
92 2009 16658 Resumo de eventos científicos N Assessment of the in vivo permanence of mGH-secreting human keratinocytes in grafted organotypic cultures
93 2009 16659 Resumo de eventos científicos N Electrotransfer of naked hGH cDNA muscle of lit/scid mouse is more efficient than genomic DNA
94 2009 16679 Resumos em periódicos I Sustained hGH expression after electrotransfer of naked DNA into DWARF 'little!' mouse skeletal muscle
95 2008 12980 Artigo de periódico I Distinct human prolactin (hPRL) and growth hormone (hGH) behavior under bacteriophage lambda Psub(L) promoter control: temperature plays a major role in protein yields
96 2008 13172 Artigo de periódico I SJL dystrophic mice express a significant amount of human muscle proteins following systemic delivery of human adipose-derived stromal cells without immunosuppression
97 2008 13173 Artigo de periódico I Evaluation of the cytogenetic effects of sup(131)I preceded by recombinant human thyrotropin (rhTSH) in peripheral lymphocytes of wistar rats
98 2008 13175 Artigo de periódico I Influence of a reduced COsub(2) environment on the secretion yield potency and N-glycan structures of recombinant thyrotropin from CHO cells
99 2008 13177 Resumos em periódicos I Sjl dystrophic mice express large amount of human muscle proteins following systemic delivery of human adipose-derived stem cells
100 2008 13178 Artigo de periódico I Secretion of mouse growth hormone by transduced primary human keratinocytes: prospects for an animal model of cutaneous gene therapy
101 2008 13661 Resumo de eventos científicos I N-glycan structures of glycoprotein hormones: a comparison between recombinant and native human pituitary thyrotropin (hTSH)
102 2008 13662 Resumo de eventos científicos I Stable expression of a human-like sialylated recombinant thyrotropin in a chinese hamster ovary cell line expressing 'alfa'2,6-sialyltransferase
103 2008 16434 Resumo de eventos científicos N Preliminary study of the cytogenetic effects of neutrons produced in reactor on human blood lymphocytes
104 2008 16598 Resumo de eventos científicos N Purification and characterization recombinant glycosylated human prolactin synthesized in cho cells
105 2008 16599 Resumo de eventos científicos N Influence of activation temperature on the degradation of recombinant proteins in E.coli
106 2008 16600 Resumo de eventos científicos I Cycloheximide increases the synthesis of recombinant glycosylated human prolactin (G-hPRL) secreted by CHO cells
107 2007 11858 Artigo de periódico I Practical reversed-phase high-performance liquid chromatography method for laboratory-scale purification of recombinant human thyrotropin
108 2007 11860 Resumos em periódicos N Growth hormone (GH) response to growth hormone-releasing peptide-2 in GH-deficient little mouse
109 2007 11949 Texto completo de evento I Evaluation of radioinduced damage an repair capacity in human breast cancer cells, MCF-7 and T-47D
110 2007 12287 Artigo de periódico I Genotoxic evaluation of [DOTA, Tyrsup(3)]octreotate labelled with sup(131)I and sup(177)Lu in human peripheral lymphocytes in vitro by micronucleus assay
111 2007 12448 Resumo de eventos científicos I Bioactive and properly folded prolactin is obtained in E.coli in a pilot bioreactor at 37 graus C by constitutive expression based on the unrepressed ?Psub(L) promoter
112 2007 12449 Resumo de eventos científicos I The effect of cycloheximide on the glycosylation of recombinant human prolactin synthesized in cho ceell
113 2007 12450 Resumo de eventos científicos I Induction of micronucleus in breast cancer cells by sup(60)Co gamma radiation
114 2007 12451 Resumo de eventos científicos I Physico-chemical characterization of alpha and beta subunit of recombinant human glycoprotein hormones: hTSH and hLH
115 2007 12452 Resumo de eventos científicos I A practical RP-HPLC method for recombinant human thyrotropin (hTSH) laboratory scale purification
116 2007 12453 Resumo de eventos científicos I Influence of reduced Co2 environment on the secretion yield, potency and glycan structures of recombinant thyrotropin (hTSH) from CHO cells
117 2007 12458 Resumo de eventos científicos I Evidence for in vivo persistence of mGH-secreting human keratinocytes by immunohistochemical staining of grafted organotpic cultures
118 2006 11409 Artigo de periódico I A molecular mimic demonstrates that phosphorylated human prolactin is a potent anti-angiogenic hormone
119 2006 11413 Artigo de periódico I HPLC analysis of human pituitary hormones for pharmaceutical applications
120 2006 11417 Artigo de periódico I Physico-chemical and biological characterizations of two human prolactin analogs exhibiting controversial bioactivity, synthesized in chinese hamster ovary (CHO) cells
121 2006 11431 Resumo de eventos científicos N Efficient separation of the two subunits of human glycoprotein hormones by high performance liquid chromatography
122 2006 11432 Resumo de eventos científicos N Enrichment of human keratinocyte stem cells and inection of naked DNA in the lit/scid mouse: studies directed to the improvement of GH gene therapy
123 2006 11433 Resumo de eventos científicos N Comparative studies of pituitary (NIDDK, USA) and recombinant (Thyrogen and IPEN) human thyroid stimulating hormone (hTSH) for what concerns cabohydrate structures and charge heterogeneity
124 2006 11435 Resumo de eventos científicos N S179D prolactin (PRL) primarity uses the extrinsic pathway and MAPkinase signaling to induced apoptosis in human endothelial cells
125 2006 11490 Artigo de periódico I Point mutation of serine 179 in the human prolactin (PRL) affects recombinant protein expression, folding and secretion, abolishes PRL nickel (II)-binding and increases heparin binding capacities
126 2006 11500 Resumo de eventos científicos I Analysis and characterization of different preparations of recombinant human follicie stimulating hormone (hFSH) and of subunits
127 2006 11501 Resumo de eventos científicos I Human prolactin (hPRL) and growth hormone (hGH) distinct behavior under bacteriophage lamdda Psub(L) promoter control
128 2006 11502 Resumo de eventos científicos I Point mutation of serine 179 in the human prolactin (PRL) affects recombinant protein expression, folding and secretion, abolishes PRL nickel (II)-binding and increases heparin binding capacities
129 2006 11541 Artigo de periódico I Analysis of intact human follicle-stimulating hormone preparations by reversed-phase high-performance liquid chromatography
130 2006 11548 Artigo de periódico I High-level secretion of growth hormone by retrovirally transduced primary human keratinocytes: prospects for an animal model of cutaneous gene therapy
131 2006 11785 Artigo de periódico I S179D prolactin primary uses the extrinsic pathway and nitogen-activated protein kinase signaling to induce apoptosis in human endothelial cells
132 2006 11814 Resumos em periódicos N Effect of recombinant TSH(rTSH) on iodine-131 residence time and dosimetry on thyroid gland: final results
133 2006 15350 Artigo de periódico I Different forms of prolactin have opposing effects on the expression of cell cycle regulatory proteins in differentiated mammary epithelial cells
134 2005 10206 Artigo de periódico I Two-step chromatographic purification of recombinant human thyrotrophin and its immunological, biological, physico-chemical and mass spectral characterization
135 2005 10585 Texto completo de evento I Genotoxic evaluation of [DOTA,Tyrsup(3)]octreotate labeled with sup(131)I and sup(177)Lu in human peripheral lymphocytes in vitro by micronucleus assay
136 2005 10605 Texto completo de evento I Efeito citogenetico do sup(131)I precedido por administracao de REC-HTSH em ratos wistar
137 2005 10865 Resumo de eventos científicos N Calculo do tempo de residencia e da atividade acumulada na glandula tereoide quando da aplicacao de sup(131)I precedido de TSH recombinante (rTSH): estudo experimental em ratos
138 2005 10866 Resumo de eventos científicos N Calculo do tempo de residencia e da atividade acumulada na glandula tereoide quando da aplicacao de sup(131)I precedido de TSH recombinante (rTSH): estudo experimental em ratos
139 2005 11001 Artigo de periódico I Animal models for growth hormone gene therapy
140 2005 11004 Capítulo de livro N Cromatografia de imunoafinidade
141 2005 11006 Resumo de eventos científicos I Practical two-step purification of recombinant human prolactin and two analogous expressed by chinese hamster ovary (CHO) cells
142 2005 11008 Resumo de eventos científicos N Analysis of human thyroid stimulating hormone (hTSH) obtained in CHO cells under different culture conditions
143 2005 11009 Resumo de eventos científicos I High-level secretion of growth hormone by retrovirally transduced primary human keratinocytes: prospects for an animal model of cutaneous gene therapy
144 2005 11010 Resumo de eventos científicos N A reversed-phase high performance liquid chromatography method for the analysis of different preparations of human follicle stimulating hormone
145 2005 11011 Resumo de eventos científicos I Reversed-phase high performance liquid chromatography (RP-HPLC) analysis and hydrophobicity studies of recombinant human pituitary hormones synthesized in E. coli and CHO cells
146 2005 11120 Texto completo de evento N Filmes polimericos a base PHB e PHB-V utilizados como sistemas de liberacao controlada de hormonio de crescimento humano recombinante
147 2004 10050 Resumo de eventos científicos N Induction of micronucleus by [DOTA, TYRsub(3)] octreotate labeled with 131I and 177Lu in peripheral blood lymphocytes in vitro
148 2004 10051 Resumo de eventos científicos N Cytogetetic effects of 131I administered with recombinant human thyrotropin hormone (Rec-HTSH) on blood lymphocyte wistar rat
149 2004 10052 Resumo de eventos científicos N Effect of recombinant TSH(RTSH) on iodine-131 residence time on thyroid gland: an experimental study in rats
150 2004 10053 Resumo de eventos científicos I Coculture studies Ba/F3-LP cells and HPRL, G129R-HPRL and S179D-HPRL secreting cho cells
151 2004 10862 Resumo de eventos científicos I Effect of recombinant TSH (rTSH) on iodine-131 residence time on thyroid gland: An experimental study in rats
152 2004 10863 Resumo de eventos científicos I Induction of micronucleus by [DOTA, Tyr3]octreotate labeled with sup(131)I and sup(177)Lu in peripheral blood lymphocytes IN VITRO
153 2004 10864 Resumo de eventos científicos I Cytogenetic effects of sup(131)I administered with recombinant human thyrotropin hormone (rec-hTSH) on blood lymphocyte of Wistar rat
154 2003 08961 Artigo de periódico I Determination of Chinese hamster ovary cell-derived recombinant thyrotropin by reversed-phase liquid chromatography
155 2003 09134 Artigo de periódico I Synthesis and chromatographic purification of recombinant human pituitary hormones
156 2003 09744 Artigo de periódico I Increases in weight of growth hormone-deficient and immunodeficient (lit/scid) dwarf mice after grafting of hGH-secreting, primary human keratinocytes
157 2003 09785 Artigo de periódico I Periplasmic expression of human growth hormone via plasmid vectors containing the lambdaPsub(L) promoter: use of HPLC for product quantification
158 2002 08536 Resumo de eventos científicos N Laboratory production and first characterization of purified recombinant human thyrotropin - IPEN
159 2002 08537 Resumo de eventos científicos N Approaches to maximizing the periplasmic expression in Escherichia coli of the human growth hormone gene from a vector containing the lambda Psub(L)
160 2002 08538 Resumo de eventos científicos N High-level expression of mouse growth hormone (mGH) by primary human keratinocytes using a retroviral vector
161 2002 08648 Artigo de periódico I High-level expression of human thyroid-stimulating hormone in Chinese hamster ovary cells by co-transfection of dicistronic expression vectors followed by a dual-marker amplification strategy
162 2002 08649 Artigo de periódico I Reversed-phase high-performance liquid chromatography method for the determination of prolactin in bacterial extracts and in its purified form
163 2002 08904 Resumo de eventos científicos I Lit/lit mice release growth hormone (GH) in response to GH releasing peptide-2 (GHRP-2) administration
164 2001 07731 Resumo de eventos científicos N Utilization of reversed-phase high performance liquid chromatography (RP-HPLC) for the analysis of recombinant thyrotropin directly in CHO cell conditioned medium
165 2001 07732 Resumo de eventos científicos N Retrovirus-mediated transfer of growth hormone gene into primary human keratinocytes produces measurable circulatory levels of the hormone in immunodeficient-dwarf mice
166 2001 07733 Resumo de eventos científicos N Rec-hPRL production in E.coli periplasmic space with the use of a temperature sensible promoter
167 2001 07734 Resumo de eventos científicos N Physico-chemical study on the First International Standard of Recombinant Human Prolactin, carried out at IPEN-CNEN/SP in collaboration with WHO
168 2000 06990 Resumo de eventos científicos N Hollow fiber bioreactors for hormone production in CHO cells
169 2000 06991 Resumo de eventos científicos N A novel, high yield purification of recombinant authentic human prolactin hormone
170 2000 06992 Resumo de eventos científicos N Purification of a recombinant protein by high performance size exclusion chromatography (HPSEC), directly from bacterial periplasmic extracts, for immunoassay reagent preparation
171 2000 06993 Resumo de eventos científicos N Utilization of di and tricistronic vectors for the expression of recombinant human thyrotropin (rec -hTSH) in CHO cells
172 2000 06994 Resumo de eventos científicos I High level synthesis of recombinant human prolactin in CHO cells and identification of the 22 kDa fragment hPRLsub(11-199)
173 2000 06995 Resumo de eventos científicos I A reversed-phase high -performance liquid chromatography (RP-HPLC) method for the determination of human prolactin (hPRL) in osmotic shock fluids and in purified preparations
174 2000 07063 Artigo de periódico I High-level synthesis of human prolactin in Chinese hamster ovary cells
175 2000 07064 Artigo de periódico I Single-step purification of recombinant human growth hormone (hGH) directly from bacterial osmotic shock fluids, for the purpose of sup(125)I-hGH preparation
176 1999 07347 Artigo de periódico I High-yield purification of biosynthetic human growth hormone secreted in Escherichia coli periplasmic space
177 1999 07722 Resumo de eventos científicos N Expression of recombinant human thyrotropin (REC-hTSH) in CHO cells using dicistronic mRNA expression vectors with amplifiable markers
178 1999 07723 Resumo de eventos científicos N Analysis of recombinant humam prolactin (REC-hPRL) directly in E.coli osmotic shock fluids
179 1999 07724 Resumo de eventos científicos N Bacterial expression and purification of a cytoplasmic form of human prolactin: a study on the utilization of different vector elements
180 1999 07725 Resumo de eventos científicos N Isolation and purification of biosynthetic human prolactin expressed in the Escherichia coli periplasmic space
181 1999 07726 Resumo de eventos científicos N High-level expression of human growth hormone (hGH) in transduced primary human keratinocytes
182 1999 07735 Artigo de periódico I Use of radioiodine urinalysis for effective thyroid blocking in the first few hours post exposure
183 1999 07736 Artigo de periódico N Gonadotrophin profiles and ovulation rate of Mantiqueira cows passively immunized against bovine follicular fluid
184 1998 06130 Artigo de periódico I Synthesis and characterization of recombinant, authentic human prolactin secreted into the periplasmic space of Escherichia coli
185 1998 07719 Resumo de eventos científicos N Solubilization, renaturation and high performance size exclusion chromatography (HPSEC) quality control of a cytoplasmic form of recombinant human prolactin
186 1998 07720 Resumo de eventos científicos N Purification of glycosylated and nonglycosylated recombinant human prolactin produced by chinese hamster ovary cells in a hollow fiber bioreactor
187 1998 07721 Resumo de eventos científicos N One-step purification of recombinant human growth hormone (REC-hGH) directly from bacterial osmotic shock fluids for the purpose of radioimmunoassay (RIA) tracer preparation
188 1998 13208 Artigo de periódico I Ultrasensitive in vivo bioassay detects bioactive human growth hormone in transduced primary human keratinocytes
189 1997 06128 Artigo de periódico I Analysis of recombinant human growth hormone directly in osmotic shock fluids
190 1997 06287 Artigo de periódico I Sensitive human thyrotropin immunoradiometric assay set up by the identification and minimization of nonspecific bindings
191 1997 06345 Resumo de eventos científicos N Amplification of hTSH alphaand beta-subunit genes by PCR, using pituitary cDNA for recombinant hTSH preparation and production of the alpha-subunit in CHO cells
192 1997 06346 Resumo de eventos científicos N Quality control of recombinant human growth hormone directly in osmotic shock fluids
193 1997 06347 Resumo de eventos científicos N Strategies for achieving high-level expression of recombinant human prolactin (hPRL) in E. coli
194 1996 04689 Resumo de eventos científicos N Expression of the uncoupling protein (UCP) from rat brown adipose tissue by transplatable human epidermal cells
195 1996 04690 Resumo de eventos científicos I Gonadotrophin profiles and ovulation rate of cows passively immunized against bovine follicular fluid
196 1996 04691 Resumo de eventos científicos N Amplification of hTSH alfa and beta subunit genes by PCR, using pituitary cDNA for recombinant hTSH preparation
197 1996 04692 Resumo de eventos científicos N Aplication of a complete set of hTSH immunoradiometric assay (IRMA) reagents produced at IPEN-CNEN/SP to neonatal hypothyroidism screening programs in Latin America
198 1996 04693 Resumo de eventos científicos N Recombinant human growth hormone. Production and quality control
199 1996 04694 Resumo de eventos científicos N Ultrasensitive in vivo bioassay detects bioactive human growth hormone in transduced primary human keratinocytes
200 1996 04695 Resumo de eventos científicos N Physicochemical and immunological quality control of bacterially expressed recombinant proteins, carried out directly on osmotic shock fluids
201 1996 04696 Resumo de eventos científicos N Production and characterization of authentic human prolactin (hPRL) secreted in the periplasmic space of Escherichia coli
202 1996 04697 Resumo de eventos científicos N A study of the efficiency of different types of bacterial expression vectors based on the 'lambda Psub(L)' and 'TAC' promoters
203 1996 04698 Capítulo de livro I Minimization of nonspecific binding to improve the sensitivity of a magnetic immunoradiometric assay (IRMA) for human thyrotropin (hTSH)
204 1996 04699 Capítulo de livro I Study of antibody immobilization on different magnetic particles utilized for the radioimmunoassay (RIA) and immonoradiometric assay (IRMA) of hormones
205 1996 04700 Artigo de periódico I Production and characterization of biologically active Ala-Ser (His)sub(6)Lle-Glu-Gly_Arg-Human prolactin (tag-hPRL), secreted in the periplasmic space of Escherichia coli
206 1996 06099 Artigo de periódico I The use of recombinant human thyrotropin produced by chinese hamster ovary cells for the preparation of immunoassay reagents
207 1995 01846 Resumo de eventos científicos N Production and caracterization of biologically active GHIS-ILEGLU-GLY-human prolactin, secreted in the periplastic space of Escherichia coli
208 1995 05876 Resumo de eventos científicos N Ultrasensitive human thyrotropin (hTSH) immunoradiometric assay (IRMA) set up by the identification and minimization of nonspecific bindings
209 1995 05877 Resumo de eventos científicos N Physicochemical immunological and biological characterization of recombinant human growth hormone
210 1995 06086 Resumo de eventos científicos N Intra and interlaboratory evaluation of commercial recombinant thyrotropin for the preparation of radioassay reagents
211 1995 06087 Resumo de eventos científicos N Recombinant human thyrotropin (REC-hTSH). Development of a biotecnology product for diagnostic and therapeutic use
212 1994 05880 Resumo de eventos científicos N Baculovirus system as an alternative to express human pituitary hormones
213 1993 02154 Resumo de eventos científicos I Use of recombinant human prolactin for radioiodination and standard preparation in radioimmunoassay
214 1993 02155 Resumo de eventos científicos I A study of different magnetic particles for the obtention of locally prepared solid-phase reagents for hTSH IRMA
215 1993 02157 Resumo de eventos científicos I Filter paper-based hTSH-IRMA: assessment of optimal tracer conditions
216 1993 02159 Resumo de eventos científicos I Radioimmunologic techniques used in quantitative and qualitative analyses of recombinant human growth hormone (rec-hGH) for E. coli contaminant proteins (ECP) and hGH-related forms determination
217 1993 04603 Artigo de periódico I The use of recombinant human growth hormone for radioiodination and standard preparation in radioimmunoassay
218 1993 04635 Resumo de eventos científicos I Filter paper-based hTSH-IRMA: stability of hTSH in dried blood spots
219 1993 05309 Artigo de periódico I In vivo bioassay for the potency determination of human growth hormone in dwarf 'little' mice
220 1992 01947 Resumo de eventos científicos N Estudo das melhores condicoes na determinacao de proteinas de E.coli em produtos obtidos mediante tecnicas de DNA recombinante
221 1992 01948 Resumo de eventos científicos N Immunoradiometric assay (IRMA) for the detection of E.coli proteins in recombinant human growth hormone prepared at IPEN-CNEN/SP
222 1992 01986 Resumo de eventos científicos N Preparacao de hormonios pituitarios humanos mediante tecnicas de DNA recombinante
223 1992 04775 Resumo de eventos científicos N Utilization of dwarf mouse strain 'little' for the potency determination of recombinant human growth hormone
224 1991 03859 Texto completo de evento N Comparacao da tecnica de separacao de radioimunoensaios em fase magnetica com dois metodos de fase liquida, mediante perfis de precisao
225 1991 03884 Resumo de eventos científicos N Preparation of human prolactin by DNA-recombinant techniques
226 1991 03885 Resumo de eventos científicos N Isolation and purification of biosynthetic human growth hormone expressed in transformed E.coli cells
227 1991 03907 Texto completo de evento I Utilization of DNA-recombinant techniques for the preparation of radioimmunoassay reagents of pituitary hormones
228 1991 03908 Texto completo de evento I Interlaboratory assay performance of three thyroid-related hormones radioassays
229 1991 03909 Texto completo de evento I Setting up a Latin America reference preparation of human thy rotropin and its validation through an international interlaboratorial study
230 1991 03910 Texto completo de evento I In-house reagent preparation for the setting up of a magnetic immunoradiometric assay (IRMA) for hTSH
231 1991 04251 Texto completo de evento I The production of primary reagents for radioimmunoassay in developing countries: problems and solutions
232 1990 03876 Artigo de periódico N Producao de hormonio de crescimento humano por tecnicas de DNA recombinante
233 1989 03002 Artigo de periódico I Ultraviolet scanning densitometry for detection, quantitation and preparative elution of protein bands from unstained gels
234 1989 03384 Resumo de eventos científicos I Human thyrotropin (hTSH) extract prepared at the IPEN (Brazil): validation as a standard preparation in two types of radioligand assays
235 1989 03385 Resumo de eventos científicos I Small-scale purification of human pituitary thyrotropin (hTSH) for use in radioligand assays
236 1989 03386 Resumo de eventos científicos I Purification and characterization of human prolactin extracted from frozen pituitaries and its application to the preparation of RIA reagents
237 1989 03387 Resumo de eventos científicos I Improvement of the radioimmunoassay for human calcitonin utilizing radioiodinated tracer repurified on polyacrylamide gel electrophoresis
238 1989 03388 Resumo de eventos científicos I Magnetic separator of low cost for use in radioimmunoassay
239 1988 01649 Texto completo de evento N Purificacao de hormonio tireotrofico humano: preparacao preliminar
240 1988 03021 Série Publicação IPEN N Purificacao de hormonio tireotrofico humano: preparacao preliminar
241 1988 03046 Série Publicação IPEN N Small-scalle purification of human pituitary lutropin (hLH) for use in radioligand assays
242 1988 03048 Série Publicação IPEN N Smallscale extraction and radioiodination of human hormones for the substitution of imported radioimmunoassay reagents
243 1988 03050 Série Publicação IPEN N A thyroid measurement method for monitoring laboratory workers exposed to sup(125)I
244 1988 03221 Artigo de periódico N Improvement of reproductibility and quality control of human growth hormone radioiodination
245 1988 03222 Artigo de periódico I Results of thyroid monitoring survey carried out on workers exposed to sup(125)I in Sao Paulo, Brazil
246 1988 03253 Artigo de periódico I Stokes radius determination of radioiodinated polypeptide hormones by gel filtration
247 1988 03376 Texto completo de evento N Smallscale extraction and radioiodination of human hormones for the substitution of imported radioimmunoassay reagents
248 1987 01519 Artigo de periódico N Otimizacao da extracao de hormonio de crescimento humano a partir de hipofises congeladas
249 1987 01584 Resumo de eventos científicos N Quantitative protein elution from unstained polyacrylamide gels
250 1987 01596 Resumo de eventos científicos N Development of a radioimmunoassay for human calcitonin applied to the early diagnosis of medullary carcinoma
251 1987 01615 Resumo de eventos científicos N Evaluation of the chloramine T stoichiometric iodination of hGH, hPRL, hTSH, hcalcitonin and BSA reference preparation
252 1987 14950 Artigo de periódico N Bioensaio de hormonio de crescimento humano por incremento de peso de ratos hipofisectomizados: analise computadorizada de esquemas fatoriais 2X2
253 1986 02417 Artigo de periódico I Influence of chloramine T iodination of the biological and immunological activity of the molecular radius of the human growth hormone molecule
254 1986 02419 Resumo de eventos científicos I Quality control in protein hormone radioiodination: possible biological, immunological and structural alterations
255 1986 02424 Resumo de eventos científicos N Influence of ionic strength on the molecular radius of protein hormones: effects on unlabelled hGH and on the immunoreactivity of sup(125)I-hTSH
256 1986 02425 Resumo de eventos científicos N Desenvolvimento da tecnica de radioimmunoensaio para dosagem de tireotrofina (TSH) em extratos hipofisarios humanos
257 1986 02478 Resumo de eventos científicos N Preparation of radioiodinated hLH free of contaminating alpha-and beta-subunits
258 1986 02622 Artigo de periódico N Increased levels of hGH binding sites in liver microsomes of pregnant women
259 1986 02650 Resumo de eventos científicos N Padronizacao de uma tecnica de determinacao do raio molecular de hormonios proteicos marcados com 125-I
260 1986 02667 Resumo de eventos científicos N Efeito da temperatura sobre a dissociacao do hormonio luteotrofico humano (hLH) marcado com sup (125)I
261 1986 02684 Resumo de eventos científicos N Physico-chemical and biological properties of growth hormone extracted from canine pituitary glands
262 1985 02632 Resumo de eventos científicos N Iodination effects on the physico-chemical properties of the human growth hormone molecule
263 1985 02651 Resumo de eventos científicos N Padronizacao de uma tecnica de deteccao de sup (125)I na tiroide de trabalhadores expostos rotineiramente a este radioiosotopo
264 1985 02665 Resumo de eventos científicos N Marcacao de proteinas hormonais com sup (125)I para uso em radioensaios realizados nos laboratorios do IPEN-CNEN/Sao Paulo
265 1985 02671 Resumo de eventos científicos N The reversed electrophoresis technique for isohormone purificartion does not alter the somatotropic activity of the hGH molecule: application of a computerized 2x2 factorial bioassay
266 1984 02355 Artigo de periódico I Bioassay of HGH: Standardization of more economical assay designs
267 1984 02367 Resumo de eventos científicos N Analise computadorizada de bioensaios fatoriais 2x2 para a determinacao da potencia e dos parametros estatisticos relativos de extratos hormonais (BASSY)
268 1984 02658 Resumo de eventos científicos N Substituicao da albumina serica bovina por gelatina animal na funcao de carregador proteico de marcacao
269 1984 02663 Resumo de eventos científicos N A tecnica de eletroforese reversa em gel de poliacrilamida, aplicada a purificacao de isohormonios, nao altera a atividade somatotrofica da molecula de hormonio de crescimento humano
270 1984 02673 Resumo de eventos científicos N Radioimunoensaio de hormonio luteotrofico humano (hLH): avaliacao de reagentes produzidos no IPEN-CNEN/SP
271 1983 01439 Artigo de periódico I Human growth hormone radioiodination using different batches of sup(125)I of various ages
272 1983 01482 Texto completo de evento N Drastic chloramine-T iodination does not effect the biological, immunological and receptor activity of the human growth hormone (HGH) molecule
273 1983 01484 Texto completo de evento N Hormonio luteotrofico hipofisario humano (hLH): Extracao, purificacao e quantificacao por radioimunoensaio
274 1982 01437 Resumo de eventos científicos N Solid phase reversed radioimmunoassay of antitetanic serum, using sup(125)I labeled toxoid
275 1982 01438 Resumo de eventos científicos N A simple technique for isohormone detection and extraction by UV densitometry on polyacrylamide gel electrophoresis (PAGE)
276 1982 01472 Texto completo de evento N Resultados de um ano de controle de qualidade inter-ensaio na determinacao da imunorreatividade de extrator de hGH
277 1982 01476 Texto completo de evento N Ensaio biologico de extrator de hormonio de crescimento humano: Preparacao e calibracao de um padrao secundario e padronizacao e esquema de ensaio mais economico
278 1982 01480 Texto completo de evento I Quality control in the potency determination of hGH extracts: Radioimmunoassay and radioreceptor assay with standardized labelling and assay conditions
279 1982 01483 Texto completo de evento N Radioensaio de hHG por receptores hepaticos solubilizados de coelho
280 1981 00659 Artigo de periódico I Radioiodination of human growth hormone with characterization and minimization of the commonly defined 'Damage Products'
281 1980 01087 Resumo de eventos científicos N Reproducible labeling of HGH (IPEN) with sup(125)I of different ages, studied on polyacrylamide gel electrophoresis (PAGE)
282 1980 01091 Resumo de eventos científicos N A technique of antibodies quantification in human serum with elimination of the unspecific effects
283 1980 01192 Resumo de eventos científicos N A radiometric technique utilizing solubilized pregnant rabbit hepatocytes for HGH dosage: an increase in sensitivity
284 1979 00633 Resumo de eventos científicos I Prolonging the stability of radioiodinated human growth hormone through low specific activity labelling
285 1979 00634 Resumo de eventos científicos I A sensitive assay of human growth hormone (hGH), using on optimized concentration of rabbit liver solubilized membrane receptor and two different radioiodinated preparations
286 1979 00665 Resumo de eventos científicos I Binding of sup(125)I-human growth hormone solubilized membrane receptors from monkey liver
287 1979 01069 Resumo de eventos científicos I A study of some possible factors leading to different isohormone compositions in human growth hormone preparations
288 1979 01086 Resumo de eventos científicos N Radioligand assay of human growth hormone (HGH) using solubilized rabbit liver membrane receptors
289 1979 01092 Resumo de eventos científicos N Quality control of sup(125)I human growth hormone
290 1979 01162 Resumo de eventos científicos N The setting up of a simple monotoring technique for yield and specific radioactivity determination of radioiodinated products
291 1979 01193 Resumo de eventos científicos N Human growth hormone (HGH) assay using microsomatic hepatic receptors
292 1979 01254 Resumo de eventos científicos N Characterization of the isohormones and other proteins in eluates from the chromatographic purification of human growth hormone (HGH)
293 1978 01155 Artigo de periódico N Application of the polyacrylamide gel electrophoresis (PAGE) technique to molecular weight determination degree of purification and aggregation of different preparations of human growth hormone NIH, KABI, IEA
294 1978 01160 Artigo de periódico N Technique of separation of the complex antigen-antibody from the free antigen on polyacrylamide gel electrophoresis. Its application in radioimmunoassay and in the detection of antigenicity during and after treatment with human growth hormone
295 1978 01161 Resumo de eventos científicos I Labelling damaging and best storage conditions of two human growth hormone preparations
296 1978 01198 Resumo de eventos científicos I A study on the variability of the isohormones present in different hGH preparations
297 1978 01228 Resumo de eventos científicos N The influence of bovine serum albumim (BSA) on the chromatographic purification of labeled human growth hormone (sup(125)I-HGH)
298 1978 01280 Artigo de periódico N Terapeutica com hormonio de crescimento humano em nanismo pan-hipofisiotropico hereditario. Pesquisa e estimativa quantitativa de anticorpos
299 1976 01079 Resumo de eventos científicos N Setting up of a polyacrylamide gel electrophoresis (PAGE) technique for the qualitative and quantitative determination of antibodies anti-human growth hormone (HGH) in patients serum, for immunogenicity evaluation of HGH extracts used in the therapy of hypopituitary dwarfism
300 1976 01080 Resumo de eventos científicos N Treatment of pituitary dwarfism with human growth hormone. Detection and quantitation of antibodies anti-HGH originated during the treatment, using polyacrylamide gel electrophoresis
301 1976 01081 Resumo de eventos científicos N Comparative study of polyacrylamide gel electrophoresis of various preparations of human growth hormone, NIH, KABI (and) IEA
302 1976 01084 Resumo de eventos científicos N A new technique of radioimmunoassay (RIA) with separation of the bound from the free radioiodinated antigen on polyacrylamide gel electrophoresis (PAGE)
303 1976 01119 Resumo de eventos científicos N Identification of human growth hormone (HGH) through two different techniques of molecular weight determination: polyacrylamide gel electrophoresis and gel filtration
304 1976 01154 Resumo de eventos científicos N Different types of 'antigen-antibody complex' formed at different levels of antibody concentration, detected by polyacrylamide gel electrophoresis (PAGE)

Quadro resumo por ano e tipo de publicação gerada em tempo real a partir do registro dos dados do autor no Repositório Digital/IPEN
22/08/2017 15:27:42
Ano Periódicos Periódicos Resumos Eventos Eventos Resumos Teses / Dissertações Livros Capítulos de Livros Relatório
Técnico
Iniciação
Científica
Total
Inter. Nac. Inter. Nac. Inter. Nac. Inter. Nac. Mest. Dout. Mplo. Inter. Nac. Inter. Nac.
Total 76 9 9 3 12 14 58 114 3 2 304
2017 1 1
2016 6 1 7
2015 1 2 1 1 5
2014 4 4 3 11
2013 3 1 1 1 1 2 9
2012 6 6 5 17
2011 3 1 4 4 1 13
2010 6 8 14
2009 4 2 2 2 3 4 17
2008 5 1 3 3 12
2007 2 1 1 7 11
2006 8 1 3 4 16
2005 2 2 1 3 4 1 13
2004 4 3 7
2003 4 4
2002 2 1 3 6
2001 4 4
2000 2 2 4 8
1999 2 1 5 8
1998 2 3 5
1997 2 3 5
1996 2 1 8 2 13
1995 5 5
1994 1 1
1993 2 5 7
1992 4 4
1991 5 1 2 8
1990 1 1
1989 1 5 6
1988 2 1 2 9
1987 2 3 5
1986 1 1 1 6 9
1985 4 4
1984 1 4 5
1983 1 2 3
1982 1 3 2 6
1981 1 1
1980 3 3
1979 4 5 9
1978 3 2 1 6
1976 6 6